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1 570 272

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Application

4627113/04, 1988-11-30

(22)

Actual filing date

1988-11-30

(45)

Published

1997-10-20

(72)

Inventor

Jutilov Ju.M.Smoljar N.N.Afanas'Ev B.E.Linenko V.I.Kirichenko V.V.

1-SUBSTITUTED 5-LAURYLTRIAZOLO-[4,5-C]-PYRIDINIUM BROMIDES SHOWING ANTIMICROBE ACTIVITY Russian patent published in 1997 - IPC

Abstract SU 1570272 A1

FIELD: organic chemistry, heterocyclic compounds. SUBSTANCE: product: 5-lauryl-1-methyltriazolo-[4,5-c] -pyridinium bromide (Ia) or 5-lauryl-1-phenyltriazolo-[4,5-c] -pyridinium bromide (Ib). Compounds were synthesized by reaction of dodecyl bromide with the corresponding triazolo-[4,5-c]-pyridine at heating in solvent medium. Yield, %; m. p. C, empiric formula, LD50, mg/kg: for Ia: 96; 123-125; C18H31N4Br;, 708 ± 34.7; for Ib: 97; 214-216; C23H33N4Br; 651 ± 37.7. The synthesized compounds show antimicrobe activity and can be used in medicine. EFFECT: improved method of synthesis, increased yield. 1 tbl

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SU 1 570 272 A1

Authors

Jutilov Ju.M.

Smoljar N.N.

Afanas'Ev B.E.

Linenko V.I.

Kirichenko V.V.

Dates

1997-10-20—Published

1988-11-30—Filed

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