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RU

(11)

2 561 281

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C1

(51)

IPC

C07D213/67(2006-01-01)

C07D471/04(2006-01-01)

C07D491/56(2006-01-01)

C07D491/147(2006-01-01)

A61K31/4415(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2014137515/04, 2014-09-16

(24)

Start date

2014-09-16

(22)

Actual filing date

2014-09-16

(45)

Published

2015-08-27

(72)

Inventor

Shtyrlin Jurij Grigor'EvichShtyrlin Nikita Valer'EvichSapozhnikov Sergej Vital'EvichIksanova Al'Fija GabdulakhatovnaNikitina Elena VladimirovnaKajumov Ajrat Rashitovich

(73)

Holder

Federal'Noe Gosudarstvennoe Avtonomnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Federal'Nyj Universitet" Vpo Kfu)

ANTIBACTERIAL AGENTS BASED ON QUATERNARY AMMONIUM SALTS Russian patent published in 2015 - IPC C07D213/67 C07D471/04 C07D491/56 C07D491/147 A61K31/4415 A61P31/04 

Abstract RU 2561281 C1

FIELD: biotechnology.

SUBSTANCE: the invention relates to novel derivatives of pyridoxine of general formula (I), having high antibacterial activity. , where at R1+R2 = -C(CH3)2-, R3+R4 = -CH2N+(C8H17)2CH2-, n = 1, X = Cl, m = 0, at R1 = R2 = 3, R3+R4 = -CH2N+(C8H17)2CH2-, n = 1, X = Cl, m = 1, at R1+R2 = -C(CH3)2-, R3 = R4 = CH2N+(CH3)2C8H17, n = 2, X = Cl, m = 0, at R1 = R2 = 3, R3+R4 = CH2N+(CH3)2C8H17, n = 2, X = Cl, m = 1, at R1+R2 = -C(CH3)2-, R3 = CH2OH, R4 = CH2N+(CH3)2C8H17, n = 1, X = Br, m = 0, at R1+R2 = -C(CH3)2-, R3 = CH2OH, R4 = CH2N+(CH3)2C18H37, n = 1, X = Br, m = 0, at R1 = R2 = H, R3 = CH2OH, R4 = CH2N+(CH3)2C8H17, n = 1, X = Br, m = 1, at R1 = R2 = H, R3 = CH2OH, R4 = CH2N+(CH3)2C18H37, n = 1, X = Br, m = 1, at R1+R2 = -C(CH3)2-, R3 = CH2N+(CH3)2C8H17, R4 = 3, n = 1, X = Cl, m = 0, at R1+R2 = -C(CH3)2-, R3 = CH2N+(CH3)2C18H37, R4 = 3, n = 1, X = Cl, m = 0, at R1 = R2 = R4 = H, R3 = CH2N+(CH3)2C8H17, n = 1, X = Cl, m = 1, at R1 = R2 = R4 = H, R3 = CH2N+(CH3)2C18H37, n = 1, X = Cl, m = 1. The invention may find application in human and veterinary medicine.

EFFECT: increased efficiency of application of the compounds.

2 cl, 1 tbl, 12 ex

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RU 2 561 281 C1

Authors

Shtyrlin Jurij Grigor'Evich

Shtyrlin Nikita Valer'Evich

Sapozhnikov Sergej Vital'Evich

Iksanova Al'Fija Gabdulakhatovna

Nikitina Elena Vladimirovna

Kajumov Ajrat Rashitovich

Dates

2015-08-27—Published

2014-09-16—Filed

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