N,N-DIISOBUTYL-N′-(P-METHYLOXYTHIOBENZOYL)-OXALYLDIAMIDE SHOWING HYPOTENSIVE ACTIVITY Russian patent published in 1994 - IPC

Abstract SU 1614439 A1

FIELD: organic chemistry, thiocarboxylic acid amides. SUBSTANCE: synthesis is carried out by reaction of 2-p-methoxyphenyl-1,3-thiazoline-4,5-dione with diisobutylamine in inert solvents at 20-25 C. The yield is 40% , m. p. is 110-113 C; LD₅₀= 1000 ± 55,5 mg/kg; empirical formula is C₁₈H₂₆O₃SN₂. EFFECT: detection of compounds showing hypotensive activity in combination with hypocoagulating effect. 7 tbl

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SU 1 614 439 A1

Authors

Gagarina M.I.

Polynskaja I.V.

Pastushenkov L.V.

Anisimova N.A.

Ivin B.A.

Kuklin V.N.

Dates

1994-12-30—Published

1989-01-25—Filed