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1 678 005

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A1

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IPC

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Application

4691653/04, 1989-05-15

(22)

Actual filing date

1989-05-15

(45)

Published

1998-10-27

(72)

Inventor

Chervinskij A.Ju.Zubritskij M.Ju.Kapkan L.M.Syropjatov B.Ja.Nijazov R.Kh.Morozova T.L.

3-SUBSTITUTED DERIVATIVES OF 1-BORON-2,8,9-TRIOXA-5-AZATRI- -CYCLO-[3,3,3,0]-UNDECANE SHOWING ACTIVITY OF PLATELET AGGREGATION INHIBITOR Russian patent published in 1998 - IPC

Abstract SU 1678005 A1

FIELD: organoelemental chemistry. SUBSTANCE: invention relates to 3-substituted derivatives of 1-boron- -2,8,9-trioxa-5-azatricyclo-[3,3,3,00,5]-undecane of the formula where (1a) R is CH3 and (1b) R is NO2. Synthesis is carried out by reaction of boric acid ester with substituted triethanolamines at reagents mixing at equimolar amounts. The yield, %; m. p., C; empirical formula for compound (1a): 98.54; 172-173; C14H20BNO4; for compound (1b): 91.80; C13H17BN2O6, 243-245. Synthesized compounds show property of inhibitor of platelet aggregation. EFFECT: improved method of synthesis. 1 tbl

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SU 1 678 005 A1

Authors

Chervinskij A.Ju.

Zubritskij M.Ju.

Kapkan L.M.

Syropjatov B.Ja.

Nijazov R.Kh.

Morozova T.L.

Dates

1998-10-27—Published

1989-05-15—Filed

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