FIELD: medicine. SUBSTANCE: present invention concerns dicarboxylic acid monoamide salts, more particularly bis-(β--hydroxyethyl) β--hydroxy-β--(n-tolyloxymethyl)ethyl amine salt of fumaric acid. Said salt inhibits aggregation of thrombocytes. Preparation is carried out by reacting bis-β--hydroxyethyl) β--hydroxy-β--n-tolyl- oxymethyl)ethyl) amine with mono (n-tolyl) fumaric acid amide. Yield is 92.4%, mp is 121-123 C, emperical formula: β- with the same therapeutical index (TI=385) is by 1.7 times more effective as compared with well known agent as aggregation of thrombocytes decreases. EFFECT: more active compound. 1 tbl
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Authors
Dates
1998-09-27—Published
1989-04-25—Filed