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1 807 685

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Application

4911033/04, 1991-02-15

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Actual filing date

1991-02-15

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Published

1996-01-10

(72)

Inventor

Koz'Minykh V.O.Syropjatov B.Ja.

MALEIC ACID CYANOACETYL- OR ISOBUTYRYL HYDRAZIDE SHOWING ANTIAGGREGATIVE ACTIVITY WITH REGARD TO PLATELETS Russian patent published in 1996 - IPC

Abstract SU 1807685 A1

FIELD: organic chemistry. SUBSTANCE: product: cyanoacetyl- or isobutyryl hydrazide of maleic acid of the formula RNHCOCH-CHCOOH where R-N ≡ C-CH2NH, (CH3)2CHCONH (Ib). Ia: C7H7N3O4, m. p. is 153-154 C; Ib: C8H12N2O4, m. p. is 169-170 C. Reagent 1: cyanoacetic acid hydrazide or isobutyric acid hydrazide. Reagent 2: maleic anhydride. Reaction conditions: equimolar quantities of reagents in ethyl acetate medium, at the room temperature. Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 1 tbl

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SU 1 807 685 A1

Authors

Koz'Minykh V.O.

Syropjatov B.Ja.

Dates

1996-01-10—Published

1991-02-15—Filed

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