GLYCYRRHIZIC ACID TRIAMIDE WITH 3-AMINOQUINOLINE SHOWING ANTIDEPRESSANT ACTIVITY Russian patent published in 1994 - IPC

Abstract SU 1764302 A1

FIELD: organic chemistry. SUBSTANCE: product: [3-0-2-0-(N- β -D-gluco-pyranosyluranoyl -3-aminoquinoline) -N- b -D-glucopyranosyluranoyl-3-aminoquino-line] - 3β, 20β -11,30-dioxo-30)-(N-3-aminoquinoline)-(30-norolean-12-en, gross-formula is C69H80N6O13, m.p. is 205-210 C (with decomposition), [α]2D

0 = +60 rotatory degree (c = 0.02, methanol), yield is 70.8%. Reagent 1: glycyrrhizic acid. Reagent 2: aminoquinoline. Reaction conditions: in the medium of dimethylformamide in the presence of pyridine and dicyclohexylcarbodiimide. Synthesized compound shows antidepressant activity and can be used in medicine. EFFECT: higher efficiency. 5 ex, 4 tbl

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SU 1 764 302 A1

Authors

Baltina L.A.

Tolstikova T.G.

Popov V.G.

Davydova V.A.

Zarudij F.A.

Tolstikov G.A.

Dates

1994-06-15Published

1990-11-26Filed