FIELD: organic chemistry. SUBSTANCE: product: tetrahydrobenz(c, d)indole derivatives of the general formula (1) given in description, where R1 - H, C1-C4- alkyl; R2 - C1-C4-alkyl; R3 - C1-C4-alkoxy or NR5R6, where R5 - R6- alkyl; C1-C4 - can be H. Yield is 27-88% . Reagent 1: corresponding N-acylsubstituted derivative or N-potassium or N-triisopropylsilyl-derivative. Reagent 2: deblocking agent, for example, tetrabutylammonium or cesium fluoride. Synthesized compounds are used in medicine. EFFECT: improved method of synthesis.
| Title |
Year |
Author |
Number |
| 4-AMINO-6-SUBSTITUTED TETRAHYDROBENZ-[C,D]-INDOLES |
1992 |
- Majkl Ehdvard Flaf[Us]
- Majkl Dzhon Martinelli[Us]
- Dzhon Menert Skauz[Us]
|
RU2073672C1 |
| USE OF 6-HETEROCYCLO-4-AMINO-1,3,4,5-TETRAHYDROBENZ[CD]INDOLE USED IN VOMITING OR NAUSEA AT MOVING, PHARMACEUTICAL COMPOSITION |
1993 |
- Richard Nolan Bukher
- Majkl Ehdvard Flof
- Dehvid Ehrnst Lokhorn
- Charl'Z Dzhon Paget
- Dzhon Menert Shos
|
RU2138262C1 |
| METHOD OF SYNTHESIS OF SUBSTITUTED HEXAHYDROBENZ[CD]INDOLES |
1991 |
- Tomas Dzhozef Kress[Us]
- Marvin Robert Linna[Us]
- Majkl Dzhon Martinelli[Us]
- Barri Kertis Peterson[Us]
- Majkl Ehdvard Flaf[Us]
- Mark Mortensen Forman[Us]
|
RU2042666C1 |
| METHOD OF PRODUCING (+)-4-DI(H-PROPYL)AMINO-6-CARBAMYL-1,3,4,5-TETRAHYDROBENZO C,D -INDOLE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT |
0 |
|
SU1375128A3 |
| PROCESS FOR PREPARING HYPPURATE OF 4-(DI-N-PROPYL) ANINO- 6-AMINOCARBONYL-1,3,4,5-TETRAHYDROBENZ (CD) INDOLE |
1991 |
- Tomas Dzhozef Kress[Us]
- Dehvid Li Vari[Us]
|
RU2034837C1 |
| 4-(DI-N-PROPYL)AMINOCARBONYL-1,3,4,5-TETRAHYDROBENZ (CD) INDOLE HIPPURATE AND 4R-AND 4S-ISOMERS THEREOF |
1992 |
- Tomas Dzhozef Kress[Us]
- Dehvid Li Vari[Us]
|
RU2083561C1 |
| RING SUBSTITUTED 2-AMINO-1,2,3,4-TETRAHYDRO NAPHTHALENES OR 3-AMINOCHROMATES OR THEIR PHARMACEUTICALLY ACCEPTABLE ACID ADDITIVE SALTS AND METHOD FOR THEIR PRODUCTION |
1992 |
- Krejg Stiven Khekhstetter[Us]
- Dajan Linn Kh'Juser[Us]
- Dzhon Menert Skaus[Us]
- Robert Daniehl' Tajtus[Us]
|
RU2057751C1 |
| USE OF TETRAHYDROBENZO[CD]INDOLE-6-CARBOXAMIDES FOR VOMITING PROPHYLAXIS, PHARMACEUTICAL PREPARATIONS BASED ON THEREOF |
1994 |
- Mark Mortensen Formen
- Dzh. Dehvid Linder
|
RU2154476C2 |
| 6-HETEROCYCLIC SUBSTITUTED 4-AMINO-1,2,2A,3,4-HEXAHYDROBENZ-[CD]-INDOLES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND METHOD FOR THEIR PRODUCTION |
1992 |
- Richard Nolan Bukher[Us]
- Dehvid Ehrnst Lokhorn[Us]
- Majkl Dzhon Martinelli[Us]
- Charl'Z Dzhonson Pehjdzhet
- Dzhon Menert Skaus[Us]
|
RU2062775C1 |
| USE OF ISOXAZOLE DERIVATIVES FOR TREATMENT OF PATIENTS WITH IRRITABLE BOWEL SYNDROME (MUCOUS COLITIS) AND A PHARMACEUTICAL COMPOSITION |
1993 |
- Dzhehsvont Singkh Gidda
- Dzhon Menert Skaus
|
RU2127111C1 |
