FIELD: pharmaceutic industry. SUBSTANCE: the product is hyppurate of 4-(di-n-propyl) amino-6-aminocarbonyl- 1,3,4,5-tetrahydrobenz (cd) indole of the empirical formula C27H34N4O4 in which R and S are isomers or a racematic mixture. Reagent 1: 4-(di-n-propyl) amino-6- aminocarbonyl-1,3,4,5-tetrahydrobenz(cd)indole. Reagent 2: hippuric acid. Reaction conditions: 0-100 C, an organic solvent, preferably ethyl or isopropyl alcohol, or mixtures thereof with 5-15% by volume of water. The resulting crystalline salt can be further recrystallized from said solvents. EFFECT: improved properties of the title compound. 6 cl
| Title |
Year |
Author |
Number |
| 4-(DI-N-PROPYL)AMINOCARBONYL-1,3,4,5-TETRAHYDROBENZ (CD) INDOLE HIPPURATE AND 4R-AND 4S-ISOMERS THEREOF |
1992 |
- Tomas Dzhozef Kress[Us]
- Dehvid Li Vari[Us]
|
RU2083561C1 |
| USE OF TETRAHYDROBENZO[CD]INDOLE-6-CARBOXAMIDES FOR VOMITING PROPHYLAXIS, PHARMACEUTICAL PREPARATIONS BASED ON THEREOF |
1994 |
- Mark Mortensen Formen
- Dzh. Dehvid Linder
|
RU2154476C2 |
| 4-AMINO-6-SUBSTITUTED TETRAHYDROBENZ-[C,D]-INDOLES |
1992 |
- Majkl Ehdvard Flaf[Us]
- Majkl Dzhon Martinelli[Us]
- Dzhon Menert Skauz[Us]
|
RU2073672C1 |
| METHOD OF SYNTHESIS OF TETRAHYDROBENZ(C,D)INDOLE AGONISTS OF SEROTONIN |
1990 |
- Majkl Ehdvard Flau[Us]
- Mark Mortensen Foreman[Us]
|
RU2007393C1 |
| USE OF 6-HETEROCYCLO-4-AMINO-1,3,4,5-TETRAHYDROBENZ[CD]INDOLE USED IN VOMITING OR NAUSEA AT MOVING, PHARMACEUTICAL COMPOSITION |
1993 |
- Richard Nolan Bukher
- Majkl Ehdvard Flof
- Dehvid Ehrnst Lokhorn
- Charl'Z Dzhon Paget
- Dzhon Menert Shos
|
RU2138262C1 |
| METHOD OF PRODUCING (+)-4-DI(H-PROPYL)AMINO-6-CARBAMYL-1,3,4,5-TETRAHYDROBENZO C,D -INDOLE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT |
0 |
|
SU1375128A3 |
| 6-HETEROCYCLIC SUBSTITUTED 4-AMINO-1,2,2A,3,4-HEXAHYDROBENZ-[CD]-INDOLES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND METHOD FOR THEIR PRODUCTION |
1992 |
- Richard Nolan Bukher[Us]
- Dehvid Ehrnst Lokhorn[Us]
- Majkl Dzhon Martinelli[Us]
- Charl'Z Dzhonson Pehjdzhet
- Dzhon Menert Skaus[Us]
|
RU2062775C1 |
| METHOD OF SYNTHESIS OF SUBSTITUTED HEXAHYDROBENZ[CD]INDOLES |
1991 |
- Tomas Dzhozef Kress[Us]
- Marvin Robert Linna[Us]
- Majkl Dzhon Martinelli[Us]
- Barri Kertis Peterson[Us]
- Majkl Ehdvard Flaf[Us]
- Mark Mortensen Forman[Us]
|
RU2042666C1 |
| PYRAZOLE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS |
1991 |
- Rejmond Frenk Braun[Us]
- Dzhejms Dzheffri Khoubert[Us]
- Karen Linn Lobb[Us]
- Dehvid Ehndrju Nil[Us]
- Dzhon Kevin Ril[Us]
|
RU2076100C1 |
| PIPERIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITION SHOWING ACTIVITY AS ANTAGONIST OF OPIOID PERIPHERAL ACTION |
1992 |
- Baddi Judzhin Kantrell[Us]
- Dennis Majkl Tsimmerman[Us]
|
RU2076863C1 |
