FIELD: medicine. SUBSTANCE: the product: 3-cyano-5,4'-bipyridine 1'-oxides of the formula: wherein R1 is amino, C1-C4-monoalkylamino, С1-С4-dialkylamino, amino-C1-C4-alkylamino, di-(C1-C4-alkyl)-amino-C1-C4-alkylamino, morpholino-C1-C4-alkylamino, oxy-С2-С4-alkylamino, di-(oxy-С2-С4-alkyl)amino, C1-C4-alkoxy, oxy-С2-С4-alkoxy, dioxy-С3-С4-alkoxy, С1-С4-alkoxy-С2-С4-alkoxy or chlorine and their physiologically compatible acid addition salts having cardiotonic and vasodilating activity. Reagent 1: 3-cyano-5,4'-bipyrides. Reagent 2: peracid or hydrogen peroxide. EFFECT: improved properties of the compounds. 2 cl
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