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2 018 530

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IPC

(21) (22)

Application

5050033/13, 1992-06-19

(22)

Actual filing date

1992-06-19

(45)

Published

1994-08-30

(72)

Inventor

Popov Boris ValentinovichSmirnova Natal'Ja NikolaevnaPavlovich Tat'Jana Jur'EvnaKutsenko Nadezhda NikolaevnaSerdjuk Grigorij Nikolaevich

(73)

Holder

Popov Boris ValentinovichSmirnova Natal'Ja NikolaevnaPavlovich Tat'Jana Jur'EvnaKutsenko Nadezhda NikolaevnaSerdjuk Grigorij Nikolaevich

STRAIN OF HYBRID CULTURED MAMMALIAN CELLS MUS MUSCULUS L USED FOR PREPARING OF MONOCLONAL ANTIBODIES TO GLYCOPROTEIN ANTIGEN 70 KDA OF CATTLE PERIPHERAL BLOOD MONONUCLEARS Russian patent published in 1994 - IPC

Abstract RU 2018530 C1

FIELD: biotechnology. SUBSTANCE: method involves the preparing of strain of hybrid cultured mammalian cells Mus musculus L. producing monoclonal antibodies to the glycoprotein antigen of cattle peripheral blood mononuclears. Molecular mass of antigen is 70 kDa. Strain is prepared by hybridization of murine splenocytes (strain BALB/c) with myeloma cells NSO. Monoclonal antibodies are IgM-class. Stable production of antibodies is retained in vitro for 10 passages. Monoclonal antibodies can be used for detection and study of membrane-bound antigens of cattle peripheral blood mononuclears. EFFECT: preparing of strain indicated above.

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RU 2 018 530 C1

Authors

Popov Boris Valentinovich

Smirnova Natal'Ja Nikolaevna

Pavlovich Tat'Jana Jur'Evna

Kutsenko Nadezhda Nikolaevna

Serdjuk Grigorij Nikolaevich

Dates

1994-08-30—Published

1992-06-19—Filed