FIELD: biotechnology. SUBSTANCE: method involves the preparing of strain of hybrid cultured mammalian cells Mus musculus L. producing monoclonal antibodies to glycoprotein antigen of cattle peripheral blood mononuclears. Molecular mass of antigen is 70 kDa. Strain is prepared by hybridization of murine splenocytes (strain BALB/c) with myeloma cells NSO. Monoclonal antibodies are IgG-class. Stable production of antibodies is retained in vitro for 10 passages. Monoclonal antibodies can be used for detection and study of membrane-bound antigens of cattle peripheral blood mononuclears. EFFECT: preparing of strain indicated above.
| Title | Year | Author | Number |
|---|---|---|---|
| STRAIN OF HYBRID CULTURED MAMMALIAN CELLS MUS MUSCULUS L USED FOR PREPARING OF MONOCLONAL ANTIBODIES TO GLYCOPROTEIN ANTIGEN 70 KDA OF CATTLE PERIPHERAL BLOOD MONONUCLEARS | 1992 |
|
RU2018530C1 |
| STRAIN OF HYBRIDOUS CULTURED MAMMALIAN CELLS MUS MUSCULUS L, PRODUCING MONOCLONAL ANTIBODIES FOR SURFACE PROTEIN OF CATTLE CORONAVIRUS | 0 |
|
SU1661231A1 |
| MEDICINAL PREPARATION TO PREVENT TRANSPLANT DETACHMENT, MONOCLONAL ANTIBODY TO CD3 ANTIGEN OF HUMAN T-LYMPHOCYTES, HYBRIDOME AND METHOD TO TREAT PATIENTS SUFFERING ACUTE TRANSPLANT DETACHMENT REACTION FOLLOWING KIDNEY TRANSPLANTATION | 2000 |
|
RU2179862C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus musculus L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING VP40 PROTEIN OF MARBURG VIRUS, (Popp STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC SYSTEM FOR EXPOSING VP40 MATRIX PROTEIN OF MARBURG VIRUS (Popp STRAIN) | 2008 |
|
RU2395575C1 |
| STRAIN 8C12 OF PERMANENT INTER-SPECIES HYBRID LINE OF CELLS OF MOUSE Mus. musculus AND SHEEP Ovis aries - PRODUCENT OF MONOCLONAL ANTIBODIES TO GLYCOPROTEIDAL ANTIGEN OF VIRUS OF CATTLE LEUCOSIS | 2008 |
|
RU2377297C1 |
| MONOCLONAL ANTIBODY SPECIFIC FOR EBOLA VIRUS | 2018 |
|
RU2705763C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus musculus 2B8 - PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO Yersinia pestis V ANTIGEN | 2011 |
|
RU2478704C1 |
| STRAIN OF HYBRID CULTIVATED CELLS OF ANIMALS Mus Musculus, PRODUCING MONOCLONAL ANTIBODIES, SPECIFIC TO PEPTIDE, WHICH POSSESSES APOPTOTIC ACTIVITY WITH RESPECT TO CANCER CELLS | 2009 |
|
RU2402605C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus musculus 5G6 - PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO Yersinia pestis V ANTIGEN | 2011 |
|
RU2478703C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus musculus L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING VP40 PROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC TEST SYSTEM FOR EXPOSING VP40 PROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) | 2008 |
|
RU2395577C1 |
