FIELD: organic chemistry, antibiotics. SUBSTANCE: product - oleandomycinoxylin of the formula I given in description. Compounds of the formula (I) show antibacterial activity, value of minimal inhibitory concentration (MIC) = 0.2-16.0 mcg/ml. Reagent 1: oleandomycins of the formula II given in description. Reagent 2: 4-6-molar excess of hydroxylamine hydrochloride. Process conditions: at pyridine excess, at the room temperature, for 2-40 h. EFFECT: improved method of synthesis. 3 tbl
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