POLYMERIC DERIVATIVE OF AMINOGLYCOSIDE ANTIBIOTICS ON THE BASIS OF N-2-(2-HYDROXYPROPYL)-METHACRYLAMIDE COPOLYMERS AS SUBSTANCES WITH ENHANCED ANTIMICROBIAL ACTIVITY Russian patent published in 1994 - IPC

Abstract RU 2021289 C1

FIELD: antibiotics. SUBSTANCE: products: polymeric derivatives of aminoglycosids on the basis of N-(2-hydroxypropyl)-methacrylamide copolymers of the general formula (image), where A - a residue of aminoglycoside antibiotic of order containing kanamycin, gentamycin; X - Gly-; Gly-Leu-; Gly-Phe-Leu-; l= 75-96 mol. %, m=3.5-15.5 mol.%, n=0.5-17.5 mol.%; mol. mass = (30-40)·103. Product shows enhanced antimicrobial activity and used in medicine. EFFECT: enhanced effectiveness of products. 3 tbl

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RU 2 021 289 C1

Authors

Nazarova O.V.

Ulbrikh Karel[Cs]

Panarin E.F.

Chetverikova T.D.

Afinogenov G.E.

Strokhalm Irzhi[Cs]

Dates

1994-10-15Published

1991-07-17Filed