METHOD FOR PREPARING FIBRE POLYMERIC COMPOSITES WITH ANTIMICROBIAL ACTIVITY Russian patent published in 2013 - IPC A61L31/12 A61P31/00 

FIELD: medicine.

SUBSTANCE: invention relates to macromolecular compound chemistry, to preparing polymeric compositions of fibre materials with the antimicrobial properties. The method consists in immobilising a bioactive polymeric complex of (N-(2-hydroxypropyl)methacrylamide-acrylic acid + gentamicin base) copolymer on phosphorus cellulose or carbon fibre materials. The method involves sorption for 24 hours at temperature 25°C from aqueous solutions of the various (0.06-0.5%) concentrations of the polymeric complex on the phosphorylated cellulose or carbon fibre materials containing the functional phosphorus groups in the acid or salt forms on its surface. The polymeric complex is attached in the structure of the fibre material with additional thermal processing at 90°C for 1.5 hours.

EFFECT: invention provides the biological compatibility of the material that exhibit the haemostatic, thromboresistant, antibacterial properties.

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