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Application

4920533/04, 1991-03-25

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Actual filing date

1991-03-25

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Published

1994-12-15

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Inventor

Bakibaev A.A.Gorshkova V.K.Shtrykova V.V.Tignibidina L.G.Saratikov A.S.Filimonov V.D.Podterebina T.V.Krjukova E.V.Krauin'Sh M.P.Akhmedzhanov R.R.Novozheeva T.P.

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Holder

Individual'No-Chastnoe Predprijatie

N,N-DI- (BENZHYDRYL) -N-(TRIFLUOROACETYL)- UREAS SHOWING ANTICONVULSANT AND ENZYME-INDUCING ACTIVITY Russian patent published in 1994 - IPC

Abstract RU 2024501 C1

FIELD: organic chemistry. SUBSTANCE: product - N,N-di- (benhydryl) -N- (trifluoroacetyl)- ureas of the formula (RC6H4)(C6H5)CHNHCON(COCF3)CH(C6H5)(C6H4R) where R - H, Cl, empirical formulas C29H23O2N2F3 and C29H21O2N2Cl2F3, m. p. are 118-120 C and 117-119 C, yield is 78% . Reagent 1: N,N-di-(benzhydryl)-urea. Reagent 2: trifluoroacetic acid anhydride. Reaction conditions: at 65-70 C, medium - benzene or its alkyl-homolog, ratio of reagent 1:reagent 2:medium = 0.01:(0.015-0.030): (0.1-0.2). Synthesized compounds are used in medicine. EFFECT: improved method of synthesis.

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RU 2 024 501 C1

Authors

Bakibaev A.A.

Gorshkova V.K.

Shtrykova V.V.

Tignibidina L.G.

Saratikov A.S.

Filimonov V.D.

Podterebina T.V.

Krjukova E.V.

Krauin'Sh M.P.

Akhmedzhanov R.R.

Novozheeva T.P.

Dates

1994-12-15—Published

1991-03-25—Filed

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