FIELD: organic chemistry. SUBSTANCE: products: new chemical compounds - bromoderivatives of N-benzhydryl-N'-(trifluoroacetyl)-ureas of the formula: (Ph)(RPh)CH-NHCONHCO-CF3 where R - o-, m-, p-Br. Empirical formula for ortho-isomer is C16H12Br N2F3O2, m. p. is 111-112 C; empirical formula for meta-isomer is C16H12Br N2F3O2, m. p. is 120-121 C; empirical formula for para-isomer is C16H12Br N2F3O2, m. p. is 117-118 C. Synthesized compounds show anticonvulsant activity. EFFECT: improved method of synthesis. 1 ex, 3 tbl
Title | Year | Author | Number |
---|---|---|---|
N-BENZHYDRYL-N'-(TRIFLUOROACETYL)-UREA SHOWING ANTICONVULSIVE ACTIVITY, AND A METHOD OF ITS SYNTHESIS | 1991 |
|
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SU1829341A1 |
N,N-DI- (BENZHYDRYL) -N-(TRIFLUOROACETYL)- UREAS SHOWING ANTICONVULSANT AND ENZYME-INDUCING ACTIVITY | 1991 |
|
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2-N-METHYLAMINO-5-CHLOROBENZHYDRYLUREA SULFATE SHOWING ANTICONVULSIVE ACTIVITY | 1991 |
|
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MALONATES OF N-AMINOACYL DERIVATIVES OF N-SUBSTITUTED UREAS HAVING ANTISPASMODIC EFFECT | 0 |
|
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PROCESS FOR PRODUCING ESTERS OF N-(2-AMINOBENZHYDRYL)-ALPHA-,BETA-,GAMMA-AMINO ACIDS AND DIPEPTIDES | 0 |
|
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METHOD OF SYNTHESIS OF 5-CHLORO-2-AMINO-SUBSTITUTED BENZHYDRYLUREAS | 1990 |
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N,N-DIALKYLSUBSTITUTED 1-NITRONAPHTHALENE-5-SULFAMIDES AS SEMIPRODUCTS FOR SYNTHESIS OF 1-AMINONAPHTHALENE-5-SULFAMIDES | 1989 |
|
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METHOD OF PREPARING N-(2-AMINOBENZHYDRYL)-GLYCIN ESTERS | 0 |
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N-CYCLOZIDES OF BENZYHYDRYLURENA EXHIBITING ANTISPASMODIC ACTIVITY | 0 |
|
SU675790A1 |
Authors
Dates
1996-12-10—Published
1991-06-17—Filed