FIELD: organic chemistry. SUBSTANCE: product: 1-(3-mercapto-[2S]-methylpropionyl)-pyrrolidine-[2S]-carboxylic acid, m. p. is 106-108 C, yield is 92% . Reagent 1: 1-(3-rhodanido-[2S]-methylpropionyl)-pyrrolidine-[2S]-carboxylic acid. Reaction conditions: catalytic hydrogenation on Pd/C at 50-120 C, under pressure 105-107 Pa. EFFECT: improved method of synthesis.
Title | Year | Author | Number |
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Authors
Dates
1995-01-09—Published
1991-09-20—Filed