FIELD: medicine, in particular, rheumatology. SUBSTANCE: essence of this method resides in studying blood B-lymphocytes, determining activity of nuclear chromatin after incubation in presence of liposaccharide and prednisolone and in presence of liposaccharide, calculating ratio between first and second figures, and diagnosing favorable progress of disease if this ratio is 0.89 and below and unfavorable progress of disease if above ratio if 1.09 and over. EFFECT: higher accuracy of diagnosis. 3 tbl
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