CIS-CHLORO-N′-((2′--TETRAHYDROFURYL)-5-FLUOROURACILATODIAMMIN- -PLATINUM (II) SHOWING ANTITUMOR ACTIVITY Russian patent published in 1995 - IPC

Abstract RU 2028301 C1

FIELD: organometallic compounds. SUBSTANCE: product - cis-chloro-N′-((2′--tetrahydrofuryl)-5-fluorouracilatodiammin- -platinum (II), yield is 65-70% , mol. mass is 463,75, at 218 C product is melted with decomposition. Reagent 1: [Pt(NH3)2Cl2]. Reagent 2: N′-((2′--tetrahydrofuryl)-5-fluorouracil. Reaction conditions: in aqueous-alkaline medium, at heating on the water bath. Synthesized compound is used in medicine. EFFECT: improved method of synthesis. 2 tbl

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RU 2 028 301 C1

Authors

Mogilevkina M.F.

Shipachev V.A.

Sidorik Evgenij Petrovich

Burlaka Anatolij Pavlovich

Korchevaja Lidija Mikhajlovna

Dates

1995-02-09Published

1992-04-16Filed