FIELD: organometallic compounds. SUBSTANCE: product - cis-chloro-N′-((2′--tetrahydrofuryl)-5-fluorouracilatodiammin- -platinum (II), yield is 65-70% , mol. mass is 463,75, at 218 C product is melted with decomposition. Reagent 1: [Pt(NH3)2Cl2]. Reagent 2: N′-((2′--tetrahydrofuryl)-5-fluorouracil. Reaction conditions: in aqueous-alkaline medium, at heating on the water bath. Synthesized compound is used in medicine. EFFECT: improved method of synthesis. 2 tbl
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Authors
Dates
1995-02-09—Published
1992-04-16—Filed