FIELD: chemistry.
SUBSTANCE: described is the improved method of obtaining cis-diammino(1,1-cyclobytanedicarboxylate)platinum(II) which relates to the compound of metals of the platinum group(MPG), in particular to the synthesis of the compounds of platinum, namely, to the synthesis of the compound cis-diammino(1,1-cyclobytanedicarboxylate)platinum(II), which is the biologically active coordination compound of platinum and can be used as the active substance of antitumorigenic medicine. The method is achieved by processing the cis-isomer of the ammine complex of platinum(II) Pt(NH3)2X2 (where X - Cl, Br, I) by the oxide or hydroxide of silver and cyclobutane-1,1-dicarboxylic acid, separation of the sediment of the insoluble salt of silver from the solution and by crystallisation of cis-diammino(1,1-cyclobytanedicarboxylate)platinum(II).
EFFECT: simplification of obtaining a high quality product.
1 cl, 3 ex, 1 tbl
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|---|---|---|---|
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RU2538895C2 |
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