FIELD: medicine; pharmacology, particularly, methods for manufacture of biologically active medicines. SUBSTANCE: essence of this method resides in repeatedly washing off leeches in distilled water and physiologic salt solution. Further steps are freezing, lyophilizing, separating skin tissue by special techniques, grinding to powder and using resultant product in tests on animals either in the form of powder or suspension in physiologic salt solution. Disclosed preparation may be administered per os or subcutaneously, intramuscularly or intravenously in the form of aqueous extracts. EFFECT: higher biological activity of end product.
Title |
Year |
Author |
Number |
METHOD OF PREPARING OF BLOOD PLASMA KALLIKREIN INHIBITOR |
1992 |
- Baskova Izol'Da Porfir'Evna
|
RU2033174C1 |
METHOD FOR PREPARING SECRETION OF SALIVARY GLANDS OF MEDICINAL LEECHES CAPABLE OF INHIBITING ADHESION AND AGGREGATION OF THROMBOCYTES, DIMINISHING RHEOLOGICAL QUALITIES OF BLOOD AND PRODUCING IMMUNITY STIMULATING EFFECT |
1994 |
- Baskova Izol'Da Porfir'Evna
|
RU2045954C1 |
PREPARATION FROM LEECH AND METHOD FOR PRODUCTION THEREOF |
2003 |
- Baskova Izol'Da Parfir'Evna
- Bazin Aleksandr Viktorovich
- Kopyl'Tsov Viktor Viktorovich
|
RU2271821C2 |
TREATMENT-AND-PROPHYLAXIS COMPOSITION FOR TAKING CARE OF SKIN AND TREATING SKIN DISEASES |
2004 |
- Devjataev Aleksandr Mikhajlovich
- Egorova Svetlana Nikolaevna
|
RU2273490C2 |
BIOLOGICALLY ACTIVE ADDITIVE FOR COSMETIC PRODUCTS AND A METHOD FOR PREPARATION THEREOF |
2001 |
|
RU2238713C2 |
METHOD OF PREPARING THE ANTIPROCOAGULATING PREPARATION FROM MEDICINAL LEECH |
1994 |
- Nikonov Gennadij Ivanovich[Ru]
- Titova Elena Aleksandrovna[Ru]
- Seleznev Konstantin Georgievich[Ua]
|
RU2101019C1 |
METHOD OF PREPARING ENZYME DESTABILASE SHOWING FIBRINOLYTIC, THROMBOLYTIC, ENDO- AND EXO-GAMMA)-LYS-ISOPEPTIDASE AND AMIDOLYTIC ACTIVITY |
1994 |
- Sverdlov E.D.
- Baskova I.P.
- Zavalova L.L.
- Luk'Janov S.A.
- Barsova E.V.
- Bogdanova E.A.
|
RU2112528C1 |
RECOMBINANT PLASMID DNA pET15/N-Dest+ AND METHOD FOR THE PREPARATION, THE STRAIN OF ESCHERICHIA COLI BL21(DE3)GOLD, TRANSFORMED BY RECOMBINANT DNA pET15/N-Dest+, AND A METHOD OF ITS RECEPTION, A METHOD FOR OBTAINING RECOMBINANT BIFUNCTION ENZYME - DESTABILASE OF MEDICAL LEECH |
2015 |
- Lazarev Vasilij Nikolaevich
- Manuvera Valentin Aleksandrovich
- Kurdyumov Aleksej Sergeevich
- Akhaev Dmitrij Nikolaevich
- Baskova Izolda Parfirevna
|
RU2658429C2 |
PHARMACEUTICAL COMPOSITION POSSESSING ANTITHROMBOTIC, THROMBOLYTIC, IMMUNOMODULATORY, ANTI-INFLAMMATORY ACTION, NORMALISING LIPID AND CARBOHYDRATE METABOLISM |
2012 |
- Baskova Izol'Da Parfir'Evna
- Zheltukhin Nikolaj Konstantinovich
- Skachilova Sofija Jakovlevna
- Kopyl'Tsova Valentina Gavrilovna
- Timokhina Irina Alekseevna
- Bazin Aleksandr Viktorovich
|
RU2519741C2 |
COSMETICS-DESTINATION BIOLOGICALLY ACTIVE ADDITIVE |
2001 |
|
RU2238718C2 |