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(19)

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2 101 019

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(51)

IPC

(21) (22)

Application

94031069/14, 1994-08-24

(22)

Actual filing date

1994-08-24

(45)

Published

1998-01-10

(72)

Inventor

Nikonov Gennadij Ivanovich[Ru]Titova Elena Aleksandrovna[Ru]Seleznev Konstantin Georgievich[Ua]

(73)

Holder

Meditsinskaja Kollektivnaja Nauchno-Vnedrencheskaja Firma

METHOD OF PREPARING THE ANTIPROCOAGULATING PREPARATION FROM MEDICINAL LEECH Russian patent published in 1998 - IPC

Abstract RU 2101019 C1

FIELD: medicine, bioactive substances. SUBSTANCE: method involves leeches freezing, lyophilization and the following milling, dilution with water, acidification to pH = 5.8-7.0, heating on boiling water bath for 3-15 min followed by filtrate collection. Preparation shows antithrombic activity, prolongs plasma recalcification time, inhibits aggregation and adhesion of platelets due to the presence of leech prostaglandins. EFFECT: improved method of preparing, enhanced effectiveness. 1 tbl

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RU 2 101 019 C1

Authors

Nikonov Gennadij Ivanovich[Ru]

Titova Elena Aleksandrovna[Ru]

Seleznev Konstantin Georgievich[Ua]

Dates

1998-01-10—Published

1994-08-24—Filed