PEPTIDE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS Russian patent published in 1995 - IPC

FIELD: organic chemistry. SUBSTANCE: product: derivatives of peptides of the formula (I) where R₁ H, phenyl (lower) alkoxycarbonyl, lower alkanoyl, C₁₅-C₂₀-alkanoyl, benzoyl, thienyl(lower)alkanoyl, phenyl(lower)alkenoyl substituted with alkenyl-group, phenyl(lower), alkanoyl substituted with lower alkyl-group; R₂ hydroxy-group; R₃ carboxy or lower alkoxycarbonyl; or R₂ and R₃ are fused together and form the group of the formula -O-C(O)-; R₄ hydroxy, lower alkanoyloxy, benzyloxy; R₅ hydroxy, lower alkanoyloxy or benzyloxy; R₆ - hydroxy, lower alkanoyloxy or benzoyloxy, or lower alkoxy, and is a single or double bond. Synthesized compounds were used in biochemistry and medicine. EFFECT: improved method of synthesis. 3 dwg, 8 tbl