FIELD: chemistry of heterocyclic compounds. SUBSTANCE: product: 1-[pyrido-[3,4-b] -1,4-oxazinyl-4-yl] -1H-indoles of the formula (I) (image), where R1 H, R2 H or lower alkyl, R H, OH, benzyloxy or group of the formula (II) (image), where R4 H; R5 - lower alkyl. Composition showing capability to restore memory disorder and/or antidepressant activity contains compound (I) in the form effective oral, parenteral or internal dose from 1 to 100 mg/kg body weight/day. Compounds (I) were synthesized by cyclization of compound (III) (image) in the presence of strong base. Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 10 cl
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