[(ARYLALKYLPIPERIDINYL-4-YL)-METHYL]-2A,3,4,5-TETRAHYDRO-1-ONES OR THEIR ACID-ADDITIVE SALTS AND A METHOD OF THEIR PREPARING Russian patent published in 1995 - IPC

Abstract RU 2043989 C1

FIELD: organic chemistry. SUBSTANCE: product: compounds of the formula (I) where X hydrogen, lower alkyl, lower alkoxy, hydroxy or nitro-group; Y hydrogen or lower alkoxy-group, or interbound X and Y form the group -OCH=O; in this case position X and Y in the half of benzene ring must be adjacent; Z hydrogen, or halogen and their acid-additive salts, and n 0 or 1. These compounds show capability to inhibit acetylcholine esterase activity and can be used for memory dysfunction improvement, for example, at Alzheimer disease. EFFECT: improved method of synthesis. 9 cl, 2 tbl

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RU 2 043 989 C1

Authors

Rehjmond V.Kosli Ml.[Us]

Bettina Shpal'[Us]

Dates

1995-09-20Published

1992-06-06Filed