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2 043 116

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IPC

(21) (22)

Application

94014228/14, 1994-05-04

(22)

Actual filing date

1994-05-04

(45)

Published

1995-09-10

(72)

Inventor

Archakov Aleksandr IvanovichIvanets Nikolaj Valer'EvichKazlas Elena Vital'EvnaKovaleva Galina Gennad'EvnaKolesanova Ekaterina FedorovnaMarkin Sergej SergeevichChulkova Tamila Movsumovna

(73)

Holder

Archakov Aleksandr IvanovichIvanets Nikolaj Valer'EvichKazlas Elena Vital'EvnaKovaleva Galina Gennad'EvnaKolesanova Ekaterina FedorovnaMarkin Sergej SergeevichChulkova Tamila Movsumovna

PEPTIDE OF APO-B RECEPTOR RESPONSIBLE FOR BINDING LOW DENSITY LIPOPROTEIN Russian patent published in 1995 - IPC

Abstract RU 2043116 C1

FIELD: medicine. SUBSTANCE: 70 short overlapping peptides were synthesized on the polypropylene needles by method Pin technology and assayed by ELISA method for binding with LPLD (lipoprotein low density). Peptide N15 (hexapeptide 201-206), heptapeptide (201-207) and octapeptide (201-208) show high apo-B-binding activity. Octapeptide 201-208 CKDKSDEE shows the maximal activity. Peptide can be used as sorbent for selective LPDL binding, for construction of artificial receptor and its insertion in the cellular membranes. EFFECT: enhanced quality of peptide indicated above. 3 cl, 3 dwg

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RU 2 043 116 C1

Authors

Archakov Aleksandr Ivanovich

Ivanets Nikolaj Valer'Evich

Kazlas Elena Vital'Evna

Kovaleva Galina Gennad'Evna

Kolesanova Ekaterina Fedorovna

Markin Sergej Sergeevich

Chulkova Tamila Movsumovna

Dates

1995-09-10—Published

1994-05-04—Filed