PEPTIDE HAVING PROTECTIVE ACTION AGAINST FOOT AND MOUTH DISEASES OF AA002A STRAIN Russian patent published in 1995 - IPC

Abstract RU 2043363 C1

FIELD: agriculture. SUBSTANCE: desired peptide α-e-di-Palm)-Lys-Tyr-Ser-Ala-Gly-Gly-Met-GLy-Ard-Ard-Gly-Asp-Leu-Glu- -Pro-Len-Ala-Ala-Arg-Val-Ala-Ala-Gln-Leu-Pro is prepared by solid phase method, 4-oxymethylphenacetamidomethyl copolymer of styrene with 1 of divinylbenzene being used. Condensation is carried out with the help of dicyclohexylcarbodiimide, additive of 1-oxybenzotriasole being used. Liquid hydrogen fluorine with additives of dimethylsulfide and p-cresol is used to separate peptide from polymer carrier and to carry out final deblocking. Desired peptide is practically non-toxic, it may be used as protective agent against foot and mouth disease of A₂₂ strain. EFFECT: improves quality of desired product. 1 tbl

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RU 2 043 363 C1

Authors

Jarov A.V.

Surovoj A.Ju.

Chepurkin A.V.

Volkova T.D.

Vol'Pina O.M.

Dates

1995-09-10—Published

1992-04-28—Filed