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2 077 338

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C1

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IPC

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Application

94040941/13, 1994-11-08

(22)

Actual filing date

1994-11-08

(45)

Published

1997-04-20

(72)

Inventor

Nikishin I.V.Vishnjakov I.F.Gorshkova T.F.Strel'Tsov L.F.Zhesterev V.I.

(73)

Holder

Vserossijskij Nauchno-Issledovatel'Skij Institut Veterinarnoj Virusologii I Mikrobiologii

METHOD OF PREPARING ANTIRABIC INACTIVATED CULTURAL VACCINE Russian patent published in 1997 - IPC

Abstract RU 2077338 C1

FIELD: virology. SUBSTANCE: vaccine strain of rabies virus is grown in the transplanted saiga kidney cultured cells on serumless nutrient medium. Infectious activity of virus is 7.5-8.0 lg minimal lethal doses (MLD) 50/ml. Virus is inactivated with preparation "A-24" (1,8,3,6-diendomethylene-1,3,6,8-tetraazacyclodecane) for 18 h (not less) at its concentration in the raw 0.1-0.15%, aluminium hydroxide is added and liquid or lyophilized vaccine is prepared. EFFECT: improved method of vaccine preparing. 1 tbl

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RU 2 077 338 C1

Authors

Nikishin I.V.

Vishnjakov I.F.

Gorshkova T.F.

Strel'Tsov L.F.

Zhesterev V.I.

Dates

1997-04-20—Published

1994-11-08—Filed

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