PYRIDAZINEAMINE DERIVATIVES AND ALSO THEIR SALTS OR STEREOCHEMICAL ISOMERIC FORMS, ANTIVIRAL COMPOSITION AND HETEROCYCLIC DERIVATIVES Russian patent published in 1995 - IPC

FIELD: organic chemistry. SUBSTANCE: product: derivatives of the formula (I) where one or two carbon atoms of methylene groups can be substituted with alkyl, (C₁-C₄)-alkoxy-group-(C₁-C₄), or the same carbon methylene groups can be joined by bridge with alkane-(C₂-C₄)-diyl radical; X CH or N, every of m and n independently each of other means 1, 2, 3 and the sum m + n 3, 4 or 5; R₁ hydrogen, haloid, alkyl-(C₁-C₄); every of R₂ and R₃ independently of other means hydrogen or (C₁-C₄)-alkyl. Alk - alkane-(C₁-C₄)-diyl, every of R₄ and R₅ independently of other means hydrogen or haloid, (C₁-C₄)-alkyl, and He is selected from the group: oxadiazole, oxazole, thiazole, thiadiazole. Reagent A (): amine. Reagent B (): pyridazine derivatives, w splitting group. Process is carried out in reactive inert solvent in the presence of the base. Heterocyclic derivatives are amines of the formula A. Antiviral composition has inert solvent and pyridazineamine derivatives of the formula (I) as active substance at concentration 0.05-15 wt. -% Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 5 tbl