DERIVATIVES OF BENZIMIDAZOLE OR THEIR ADDITIVE SALTS WITH ORGANIC OR MINERAL ACIDS, OR WITH MINERAL OR ORGANIC BASES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 1996 - IPC

FIELD: organic chemistry. SUBSTANCE: product: derivatives of benzimidazole (I) where R - alkyl, alkenyl, R₁B, R₂B, R₃B, R₄B and R₅B - hydrogen; R₂B and R₅B - hydrogen; R₁B and R₃B - one hydrogen and another - CO₂R₇ and -R₁; R₇ - hydrogen, alkyl or alkenyl; R₁ - hydrogen, hydroxyl, alkylated carboxyl, radical - where Ra and Rb - hydrogen, alkyl or alkenyl. Method of synthesis of (I) involves interaction of (II) with (III) obtaining (IV) followed by removal of protecting groups. Pharmaceutical composition showing antagonistic action with regard to angiotensin II containing (I) as an active agent at effective amount. Synthesized compounds were used as drugs. ???EFFECT: improved method of synthesis. 4 cl, 1 tbl