BICYCLIC IMIDAZOLE DERIVATIVES AND METHOD OF THEIR SYNTHESIS, INTERMEDIATE COMPOUND AND METHOD OF ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION Russian patent published in 1999 - IPC

Abstract RU 2141481 C1

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes new bicyclic derivatives of imidazole of the general formula (I) where X, n, A₁,A₂,A₃,A₄,X₂ are given in p. 1 of the invention claim. Compounds show antagonistic properties for acceptor to angiotensin-II and inhibitory activity with respect to angiotensin-II. Invention describes also a pharmaceutical composition based on the compound of the formula (I), an intermediate compound and a method of its synthesis. EFFECT: improved method of synthesis, valuable pharmacological properties. 9 cl, 31 ex

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RU 2 141 481 C1

Authors

Alen Korb'E

Zhan Pol' Vever

Zhidong Zkhang

Dates

1999-11-20—Published

1994-08-04—Filed