FIELD: organic chemistry. SUBSTANCE: product: compounds of the formula (I) 
where R1 and R2 that can be similar or different and mean hydrogen atom or C1-C4-alkyl group, respectively, or form together the group of C5-C9-cycloalkane together with connected carbon atom; two X-a together form group of the formula (a) 
or (b) 
where R3 - hydrogen atom or methyl group; R4 and R5 that can be similar or different and mean hydrogen atom or C1-C4-alkyl group, respectively, or together form cyclobutane with carbon, and absolute configurations on corresponding chiral centers in constituent 4,5-bis-(aminomethyl)-1,3-dioxolane represent (4R, 5R)- or (4S,5S)-isomers, and methods of their synthesis. Intermediate products: 4,5-bis-(substituted)-1,3-dioxolanes of the formula (9) 
and (10) 
and methods of their synthesis, and use of compounds of the formula (I) 
for cancer treatment in human and animals. Reagent 1: 4,5-bis-(methanesulfonate)-1,3-dioxolane of the formula (8) 
where R1 and R2 are similar or different - hydrogen atom or C1-C4-alkyl, for exception, that both R1 and R2/ - methyl group, or R1 and R2 together with carbon atom with which they were connected form C3-C9-cycloalkyl, and absolute configurations on corresponding chiral centers represent (4R, 5R)- or (4S,5S)-isomers. Reagent 2: sodium azide. Process conditions: in medium of N,N-dimethylformamide, at 20-120 C for 1-24 hr. Reagent 3: 4,5-bis-(azidomethyl)-1,3-dioxolane of the formula (9) 
where R1 and R2 as indicated above. Reagent 4: hydrogen in the presence of palladium on coal or platinum (2+) oxide. Process conditions: in alcohol medium, under pressure 0-70 pounds per " дюйм2", at 0-50 C for 30 min-24 hr. Reagent 5: 4,5-bis-(aminomethyl)-1,3-dioxolane of the formula (10) 
where R1 and R2 as indicated above. Reagent 6: equimolar amount of tetrahalogenplatinate (2+) salt of the formula M P(Hal). Process conditions: in aqueous medium at temperature from 0 to 100 C, under atmosphere pressure or in inert gas flow. Reagent 7: complex of platinum (2+) dihalogendiamine of the formula (I) 
where X - halide. Reagent 8: acid (L)R CHOHCOOH. Reagent 9: silver (1+) oxide. Variants of proposed methods were described also. Synthesized compounds were used in medicine as antitumor agents. ??? EFFECT: improved methods of synthesis. 25 cl, 6 tbl
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