FIELD: virology. SUBSTANCE: strain of human cultured cells HTHIY27 - a producer of HIV is obtained by cloning using method of limiting dilution on fider layer. Strain shows stable cultural properties and optimally high persistent virus production (in 100% cells simultaneously) without cellular destruction. Produced virus shows high infection power for sensitive cells and has complete proteins set in immunoblotting. Strain can be used for highly sensitive and highly specific diagnostic system for AIDS, for screening antiviral preparations, and different problems associated with pathogenesis of HIV-infection. EFFECT: high properties of strain indicated above. 2 tbl, 2 dwg
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RU2046138C1 |
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