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2 068 847

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C1

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Application

94018187/04, 1994-05-18

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Actual filing date

1994-05-18

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Published

1996-11-10

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Inventor

Druzhinina V.V.Zhestkov V.P.Portnov Ju.N.Smirnov L.D.Antipov A.V.Bessudnova N.V.Bobrov V.I.Burov Ju.V.Nazarova O.I.Timashova O.A.Treskov V.G.

(73)

Holder

Vserossijskij Nauchnyj Tsentr Po Bezopasnosti Biologicheski Aktivnykh Veshchestv

DERIVATIVES OF 3,4-DIHYDRO- OR 1,2,3,4-TETRAHYDRO-β--CARBOLINES OR THEIR SALTS WITH ORGANIC OR INORGANIC ACIDS SHOWING ANTIMICROBIAL ACTIVITY Russian patent published in 1996 - IPC

Abstract RU 2068847 C1

FIELD: organic chemistry. SUBSTANCE: product: derivatives of 3,4-dihydro- or 1,2,3,4-tetrahydro-β--carbolines substituted with alkyl, acyl, carboxyl, alkoxy, hydroxy or bromine. Reagent 1: 3-(2-aminoethyl)-indole. Reagent 2: corresponding carboxylic acid chloroanhydrides. Reaction conditions: in chloroform solution in the presence of triethylamine, at 0-5 C followed by cyclization with phosphorus oxychloride in dry dioxane. Synthesized compounds were used for synthesis of medicinal preparations showing antibacterial action. EFFECT: improved method of synthesis. 4 tbl

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RU 2 068 847 C1

Authors

Druzhinina V.V.

Zhestkov V.P.

Portnov Ju.N.

Smirnov L.D.

Antipov A.V.

Bessudnova N.V.

Bobrov V.I.

Burov Ju.V.

Nazarova O.I.

Timashova O.A.

Treskov V.G.

Dates

1996-11-10—Published

1994-05-18—Filed

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