METHOD OF SYNTHESIS OF 5-CHLORO-2-AMINO-SUBSTITUTED BENZHYDRYLUREAS Russian patent published in 1995 - IPC

Abstract RU 2030396 C1

FIELD: organic chemistry. SUBSTANCE: new method of synthesis of novel early not described derivatives of 5-chloro-2-amino-substituted benzhydrylureas. Reagent 1: urea. Reagent 2: 5-chloro-2-amino-substituted benzhydrols. Reaction conditions: reaction is carried out in concentrated sulfuric acid at the ratio of reagent 1 and 2 and sulfuric acid = (8-9):1:(4-4.3). Yield is 70-80%. Synthesized compounds were used for medicinal preparations preparing. EFFECT: improved method of synthesis. 2 tbl

Similar patents RU2030396C1

Title Year Author Number
2-N-METHYLAMINO-5-CHLOROBENZHYDRYLUREA SULFATE SHOWING ANTICONVULSIVE ACTIVITY 1991
  • Bakibaev A.A.
  • Gorshkova V.K.
  • Shtrykova V.V.
  • Tignibidina L.G.
  • Saratikov A.S.
  • Filimonov V.D.
  • Podterebina T.V.
  • Fomintseva L.G.
RU2033411C1
N-BENZHYDRYL-N'-(TRIFLUOROACETYL)-UREA SHOWING ANTICONVULSIVE ACTIVITY, AND A METHOD OF ITS SYNTHESIS 1991
  • Bakibaev A.A.
  • Gorshkova V.K.
  • Shtrykova V.V.
  • Tignibidina L.G.
  • Saratikov A.S.
  • Filimonov V.D.
  • Podterebina T.V.
  • Fomintseva L.G.
RU2033412C1
N,N-DI- (BENZHYDRYL) -N-(TRIFLUOROACETYL)- UREAS SHOWING ANTICONVULSANT AND ENZYME-INDUCING ACTIVITY 1991
  • Bakibaev A.A.
  • Gorshkova V.K.
  • Shtrykova V.V.
  • Tignibidina L.G.
  • Saratikov A.S.
  • Filimonov V.D.
  • Podterebina T.V.
  • Krjukova E.V.
  • Krauin'Sh M.P.
  • Akhmedzhanov R.R.
  • Novozheeva T.P.
RU2024501C1
BROMOSUBSTITUTED N-BENZHYDRYL-N'-(TRIFLUOROACETYL)-UREAS SHOWING ANTICONVULSANT ACTIVITY AND METHOD OF THEIR SYNTHESIS 1991
  • Bakibaev A.A.
  • Gorshkova V.K.
  • Shtrykova V.V.
  • Tignibidina L.G.
  • Saratikov A.S.
  • Filimonov V.D.
  • Podterebina T.V.
  • Malitskaja E.V.
  • Krauin'Sh M.P.
RU2070039C1
METHOD FOR PRODUCTION OF 2-AMINO-5-CHLOROBENZHYDROL, 2-N-METHYLAMINO-5-CHLORBENZHYDROL AND M-CHLOROBENZHYDROL 1992
  • Bakibaev A.A.
  • Tignibidina L.G.
  • Shtrykova V.V.
  • Filimonov V.D.
  • Bychkov I.A.
  • Sologub A.P.
  • Novozheeva T.P.
RU2065435C1
METHOD OF PREPARING M-CHLORODIPHENYL METHYLUREA 1992
  • Bakibaev A.A.
  • Tignibidina L.G.
  • Shtrykova V.V.
  • Filimonov V.D.
  • Bychkov I.A.
  • Sologub A.P.
  • Novozheeva T.P.
RU2092478C1
METHOD OF SYNTHESIS OF 1,5-DINITRO-3,7-ENDO-METHYLENE-1,3,5,7- TETRAZACYCLOOCTANE 2001
  • Lobanova A.A.
  • Il'Jasov S.G.
  • Sakovich G.V.
  • Zharkov A.S.
  • Popov N.I.
  • Sataev R.R.
  • Zolotukhin V.N.
RU2198886C1
HALOGEN-SUBSTITUTED N-BENZHYDRYL-N'-(TRIFLUOROACETYL)-UREAS SHOWING ANTISPASMODIC ACTIVITY 1991
  • Bakibaev A.A.
  • Gorshkova V.K.
  • Shtrykova V.V.
  • Tingibidina L.G.
  • Saratikov A.S.
  • Filimonov V.D.
  • Podterebina T.V.
  • Krjukova E.V.
  • Krauin'Sh M.P.
SU1829341A1
OPTIC ISOMERS OF (+) AND (-)-BENZHYDRYLUREAS AND (+) AND (-)-1-[(3-CHLOROPHENYL)-PHENYL-METHYL]UREA, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF THEREOF OBTAINING 2013
  • Khudolej Vladimir Nikolaevich
  • Doroshenko Aleksandr Sergeevich
  • Filimonov Viktor Dmitrievich
  • Shtrykova Viktorija Viktorovna
  • Kuksenok Vera Jur'Evna
RU2537361C1
METHOD OF PRODUCING 1-ADAMANTANE CARBOXYLIC ACID 2009
  • Gan'Kin Jurij Aleksandrovich
  • Kornev Mikhail Aleksandrovich
  • Rjabikova Nina Sergeevna
  • Kondjukov Ivan Zinov'Evich
  • Il'In Vladimir Petrovich
RU2412930C1

RU 2 030 396 C1

Authors

Bakibaev A.A.

Shtrykova V.V.

Tignibidina L.G.

Filimonov V.D.

Dates

1995-03-10Published

1990-10-22Filed