PROCESS FOR PREPARING [R-($$$)]-2,2-DICHLORO-N-1(FLUOROMETHYL)-2-HYDROXY-2-[4-METHYLSULFONYL)-PHENYL)ETHYLACETAMIDE AND PROCESS FOR PREPARING D-(-)THREO-2-(DICHLOROMETHYL)-4,5-(DIHYDRO-5-[4-(METHYLSULFONYL)PHENYL)-4-OXAZOLEMETHANOL Russian patent published in 1997 - IPC

Abstract RU 2071468 C1

FIELD: chemical industry. SUBSTANCE: product: phlorophenycol and new intermediate compound for preparation thereof. Stage I: reagent 1: D-threo-2-(dichloromethyl)-4,5-dihydro-5-4-(methylsulfonyl)phenyl-4-oxazolemethanol. Reagent 2: isopropanol saturated with ammonia or containing ammonium salt. Stage D: Reagent 1: D-(-)- threo-2-(dichloromethyl)-4,5-dihydro-5-4-(methylsulfonyl)phenyl-4-oxazolemethanol (new intermediate product). Reagent 2: Ishikawa reagent, Stage III: Reagent 1: (4,5)-2-dichloromethyl-5-4-methylsulfonyl)-phenyl-4-fluoromethyl-1,3-oxazoline. Reagent 2: acetic acid. EFFECT: more efficient preparation process. ex 3

Similar patents RU2071468C1

Title Year Author Number
PROCESS OF ASYMMETRIC PREPARATION OF FLORPHENYCOL, METHOD OF REGIOSELECTIVE OPENING OF CHIRAL EPOXIDE, AND PROCESS OF PREPARATION OF R,S-ISOMER THEREOF 1993
  • Guang-Zong Vu
  • Vanda I.Tormos
RU2126383C1
PROCESS FOR PREPARING 2-METHYL-3-TRIFLUOROMETHYLANILINE, TRIFLUOROMETHYLPIVALANILIDE DERIVATIVES, AND PROPECC FOR PREPARING THE SAME 1992
  • Khenri Dzh.Doran[Ie]
  • Donal'D Dzh.Kaveni[Ie]
RU2081105C1
LIQUID ANTIBACTERIAL COMPOSITION 1991
  • Khenri Ehpilian[Us]
  • Dehvid Kofajn Bich[Us]
  • Ehbju Khjukej[Us]
RU2085191C1
POLYCYCLIC GUANINE DERIVATIVES 1991
  • Bernard Nojshtadt[Us]
  • Nil Lindo[Us]
  • Brajn Mehk Kittrik[Us]
RU2080322C1
CARBONATES OF PHENICOL ANTIBIOTICS 2006
  • Glinka Tomash V.
  • Shuster Dehjl Ehdvard
  • Selli Chander Shekher
  • Simmons Robert D.
  • Zhang Dzhejson
RU2432352C2
PROCESS FOR THE PREPARATION OF 1-CARBAMOYLMETHYL-4-PHENYL-2-PYRROLIDONE 2017
  • Gorelik Mikhail Viktorovich
  • Lukyanets Evgenij Antonovich
  • Bernadskij Mark Isakovich
  • Lomzakova Vera Ivanovna
  • Belyakov Nikolaj Grigorevich
  • Kosmynina Galina Valentinovna
  • Soloveva Lyudmila Ivanovna
  • Fedorova Tatyana Mikhajlovna
  • Levin Aleksandr Aleksandrovich
RU2663899C1
PROCESS FOR PREPARING SALTS OF STEREOOISOMER 5R,6R,8R DERIVATIVES OF 2-PENEM 0
  • Styuart Volter Mekkombi
SU1053754A3
DERIVATIVES OF BIS-BENZO- OR BENZOPYRIDO-CYCLOHEPTAPIPERIDINE, PIPERIDYLIDENE AND PIPERAZINE AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 1991
  • Dzhon Pivinski[Us]
  • Majkl Grin[Us]
  • Dzhesi Vong[Us]
RU2086549C1
METHOD OF SYNTHESIS OF ARYLTRIAZOLINE 1990
  • Dzhordzh Teodoridis[Us]
  • Dzhon Uil'Jam Lajga[Us]
RU2060994C1
METHOD FOR ENANTIOMERIC ENRICHMENT OF MIXTURE OF D- AND L-TREO-2-AMINO-3-HYDROXY-3-PHENYL PROPIONIC ACIDS, OR DERIVATIVES THEREOF, OR SALTS THEREOF 1992
  • Ehndrju L.Zejtlin
  • Muppala S.Radzhu
  • Dehvid I.Stirling
RU2112805C1

RU 2 071 468 C1

Authors

Dzhon Klark[Us]

Doris Shumakher[Us]

Guang-Tsong Vu[Cn]

Dates

1997-01-10Published

1991-10-23Filed