FIELD: chemical industry. SUBSTANCE: product: phlorophenycol and new intermediate compound for preparation thereof. Stage I: reagent 1: D-threo-2-(dichloromethyl)-4,5-dihydro-5-4-(methylsulfonyl)phenyl-4-oxazolemethanol. Reagent 2: isopropanol saturated with ammonia or containing ammonium salt. Stage D: Reagent 1: D-(-)- threo-2-(dichloromethyl)-4,5-dihydro-5-4-(methylsulfonyl)phenyl-4-oxazolemethanol (new intermediate product). Reagent 2: Ishikawa reagent, Stage III: Reagent 1: (4,5)-2-dichloromethyl-5-4-methylsulfonyl)-phenyl-4-fluoromethyl-1,3-oxazoline. Reagent 2: acetic acid. EFFECT: more efficient preparation process. ex 3
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Authors
Dates
1997-01-10—Published
1991-10-23—Filed