METHOD FOR PRODUCTION OF N-ACETYL-PHENYL ALANINE METHIONINES Russian patent published in 1997 - IPC

Abstract RU 2072358 C1

FIELD: production of biologically active compounds. SUBSTANCE: desired product represents dipeptide having formula N-Ac-Phe-Met, its essential formula being C₁₆H₂₂N₂O₄S. L,D-isomer having melting point 171-172 C is prepared at yield 80 %, D,L-isomer having melting point 150-151 C is prepared at yield 43 %. Method involves hydrogenation of complex of dehydrodipeptides with CaCl₂ and FeSO₄, Pd/C being used as catalyst. EFFECT: improves efficiency of the method.

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RU 2 072 358 C1

Authors

Lisichkina I.N.

Vinogradova A.I.

Bachurina I.B.

Belikov V.M.

Dates

1997-01-27—Published

1994-08-22—Filed