CATALYST OF ASYMMETRICAL HYDROGENATION OF DEHYDROAMINO ACID AND THE METHOD OF ITS PRODUCTION Russian patent published in 2017 - IPC B01J23/44 B01J37/18 B82B3/00 

FIELD: chemistry.

SUBSTANCE: invention relates to a dispersion of palladium nanodimensional particles modified with (-)-cinchonidine, in methanol or a methanol-toluene mixture as a catalyst for asymmetric hydrogenation of double C=C bonds in unsaturated dehydroamino acids. The invention also relates to a process for the preparation of a dispersion of palladium nanodimensional particles modified with (-)-cinchonidine in methanol or a methanol-toluene mixture which comprises the reduction of palladium from a solution of the bis-acetylacetonate salt in a modifier-containing solvent at a molar ratio of the modifier to palladium 0.5-6.0.

EFFECT: use of a catalyst in the hydrogenation of N-acetyl α-amidocinnamic acid allows to obtain up to 85 percent excess of the enantiomer of N-acetyl phenylalanine.

2 cl, 3 dwg, 2 tbl, 12 ex