FIELD: biotechnology, medicine, pharmacy, veterinary science. SUBSTANCE: invention proposes the preparation based on genetic-engineering gamma-interferon (molecular mass is 16.7 kDa0 consisting of 144 amino acid residues. Preparation is prepared by microbiological synthesis followed by chromatography purification. Specific antiviral activity of preparation is 2 x 107 IU/mg protein (not less) and preparation contains 95% basic substance as monomer and 5% as dimeric form by data of PAAG-DDS electrophoresis. Preparation has biologically inert low-molecular polymeric vehicle-stabilizing agent (polyvinylpyrrolidone or dextran) and saline buffer system at pH = 4.5-7.5. Preparation can contain also amino acid arginine, histidine or lysine or its physiologically acceptable salt at amount 0.5-3%, and nonionogenic surface-active substance. EFFECT: high antiviral activity, prolonged stability during storage (at least one year). 5 cl
