ALPHA-INTERFERON PREPARATION IN THE FORM OF STABLE AQUEOUS SOLUTION FOR INJECTIONS Russian patent published in 2005 - IPC

Abstract RU 2255729 C1

FIELD: pharmaceutical chemistry.

SUBSTANCE: invention relates to drugs for prevention and treatment of a variety of viral proliferative diseases and immunity disorders. Proposed solution contains: high-purity alpha-interferon; inert polymeric filler (in particular dextran or rheopolyglucin with molecular mass of dextran 30-50 kD); nonionic surfactant: tween 80, ethylenediaminetetraacetic acid or sodium salt thereof; buffer system including sodium acetate to provide solution pH 4.5-5.5; sodium chloride as osmotic pressure regulator; and injection water, all in specified proportions.

EFFECT: prolonged high activity and stability of preparation (up to 30 months) and improved quality characteristics thereof.

2 cl, 5 tbl, 2 ex

Similar patents RU2255729C1

Title	Year	Author	Number
SOLUTION FOR INJECTION, RECOMBINANT PLASMID DNA pSX50 ENCODING SYNTHESIS OF HUMAN RECOMBINANT ALPHA-2b INTERFERON, STRAIN Escherichia coli SX50 AS INDUSTRIAL STRAIN-PRODUCER OF HUMAN RECOMBINANT ALPHA-2b INTERFERON AND METHOD FOR INDUSTRIAL PREPARING INTERFERON ALPHA-2b	2006	Mogutov Mikhail Aleksandrovich Jarotskij Sergej Viktorovich Skrypin Vasilij Ivanovich Jakovenko Andrej Romanovich Chezhgalova Nelli Anatol'Evna Selishchev Stepan Vladimirovich	RU2319502C1
PREPARATION BASED UPON HUMAN RECOMBINANT ALPHA-2-INTERFERON FOR INJECTIONS IN DRY LYOPHILIZED FORM	2002	Khomichev V.V. Vojtenko A.V. Bazhutin N.B. Targonskij S.N.	RU2236866C2
GENETIC-ENGINEERING GAMMA-INTERFERON PREPARATION	1994	Somov A.N. Cherepanov P.A. Fedjukin V.S. Pavlov V.M. Astashkina G.F. Shmatchenko N.A.	RU2077336C1
COMPOSITION OF AQUEOUS SOLUTION OF RECOMBINANT HUMAN INTERFERON ALPHA-2 FOR RECTAL ADMINISTRATION	2014	Sharypova Mar'Jana Grigor'Evna Naumova Nina Vasil'Evna Smolina Margarita Petrovna Vojtenko Aleksandr Vasil'Evich Targonskaja Oksana Viktorovna Targonskij Sergej Nikolaevich	RU2564951C1
HUMAN INTERFERON-ALPHA-TWO AQUEOUS SOLUTION FOR INJECTION	2002	Gur'Ev V.P. Gur'Eva T.L. Kolokol'Tsov A.A. Belova N.V. Zolin V.V. Agafonova O.A. Moiseenkova O.A. Degteva S.A. Bazhutina N.V. Bazhutin N.B.	RU2238758C2
PREPARATIVE FORM OF STABLE AQUEOUS SOLUTION OF INTERFERON, METHOD FOR ITS PREPARING AND USING	2000	Chzhan Lehj	RU2242242C2
COMPOSITION CONTAINING HUMAN RECOMBINANT INTERFERON ALPHA-2b, AND MEDICINAL AGENT OF PROLONGED ACTION FOR VETERINARY SCIENCE ON ITS BASIS, HAVING ANTIVIRUS AND IMMUNOMODULATORY ACTION	2009	Gavrikov Aleksej Valer'Evich Kaluzhskij Vasilij Evgen'Evich	RU2404797C1
ANTIVIRAL AGENT IN LIQUID FORM AND METHOD FOR ITS PREPARATION	2021	Markov Ilya Aleksandrovich Markova Elena Alekseevna Gaponyuk Polina Petrovna Markova Inna Nikolaevna Gaponyuk Petr Yakovlevich	RU2768656C1
METHOD OF RECOMBINANT PROTEIN LIQUID MEDICINAL FORM PREPARING	2001	Beljakov N.V. Korobitsyn L.P. Pivovarov A.M. Prokop'Ev A.A.	RU2180233C1
STABILISED IMMUNE-CORRECTIVE DRUG VIFERON-FORTE FOR TREATING INFECTIOUS-INFLAMMATORY DISEASES	2008	Malinovskaja Valentina Vasil'Evna Malinovskij Evgenij Jur'Evich Malinovskij Jurij Evgen'Evich	RU2381812C1

RU 2 255 729 C1

Authors

Cherepanov P.A.

Dates

2005-07-10—Published

2004-07-26—Filed