METHOD FOR EVALUATING CLINICAL EFFICIENCY OF USING VERAPAMYL AND DILTHIAZEM IN PATIENTS AFFECTED WITH HYPERTROPHIC CARDIOMYOPATHY Russian patent published in 1997 - IPC

FIELD: medicine, cardiology. SUBSTANCE: following parameters are measured: movement velocity parameters of mitral valve indicative of diastolic function of heart's left ventricle and beat volume of left atrium to thereby determine factor K using following formula , wherein VAC and VFA are velocities of opening and closure of mitral valve indicative of atrium's systole, and LABV is left atrium's beat volume. Cardiologist proceeds upon assumption that if factor K value is equal to, or greater than 6, it is verapamyl that is clinically effective, whereas at factor K value of below 6 it is dilthiazem that is clinically useful. EFFECT: proposed method can be used to evaluate clinical efficiency of calcium antagonists in patients affected with hypertrophic cardiomyopathy, thereby showing rational approach to their treatment.