SUBSTRATE BASED ON CELL CULTURE FOR FLAVIVIRUSES AND ARENOVIRUSES CULTURING AND METHOD OF PREPARING FLAVIVIRUS OR ARENOVIRUS ANTIGEN Russian patent published in 1997 - IPC

Abstract RU 2082757 C1

FIELD: virology. SUBSTANCE: invention relates to producing viral antigen of spring-summer meningoencephalitis (FSME) by culturing virus FSME in cell cultures depending on the surface of permanent cellular strain, preferably, vero-cellular strain ATCC CCL-81. Method involves infection with virus FSME and cells were maintained in nonlytic serumless system as bound with carriers to provide antigen formation. Then antigen-containing medium is separated from cells bound with carriers by the known method followed by concentration, inactivation and purification and treated to obtain galenic preparation. EFFECT: improved method of preparing. 6 cl

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RU 2 082 757 C1

Authors

Vol'Fgang Mundt[At]

Nel Barrett[Ie]

Fridrikh Dorner[At]

Jokhann Ajbl[At]

Dates

1997-06-27Published

1990-12-21Filed