MEDICINAL PREPARATION ON CARRIER Russian patent published in 1997 - IPC

FIELD: pharmacy. SUBSTANCE: medicinal preparations were obtained by the combined grinding an active substance and carrier at their mass ratio = 1: (0.1-100) in atmosphere of one or more solvents. Solvents can dissolve an active component or adsorb on carrier surface. Active components: griseofulvin, piroxicam, diacerine, diltiazem, megestrol acetate, nifedipin, nicergoline, ketoprofen, naproxen, diclofenac, ibuprofen, lorazepam and oxazepam. Carriers: crospoviden, polymeric netted cyclodextrin, netted carboxymethylstarch sodium, dextran, cyclodextrin and its derivatives, silica gel, titanium dioxide, aluminium oxides, polyvinylpyrrolidone, cellulose and its derivatives. Preferable ratio of an active substance to carrier = 1:(1-10) (mas. p. p.). EFFECT: increased solubility rate. 23 cl, 12 tbl