FIELD: organic chemistry. SUBSTANCE: product: (S,S)-N-(2-hydroxycyc- -lopentyl)-1-isopropyl-6-methylergoline-8-carboxamide or (S, R)-N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8- -carboxamide, their hydrates, or pharmaceutically acceptable acid-additive salts. Synthesis is carried out by action of 1-isopropyl-6-methylergoline-8-hydrazide on the corresponding 2-hydroxycyclopentylamine in acid medium. Synthesized compounds were used for arterial pressure decrease. EFFECT: improved method of synthesis. 3 cl
| Title |
Year |
Author |
Number |
| CIS-(-)-4-[(1(2)H-TETRAZOLE-5-YL)-METHYL]-2-PIPERIDINE CARBOXYLIC ACID AND PHARMACEUTICAL COMPOSITION SHOWING ACTIVITY AS AN ANTAGONIST OF EXCITEMENT AMINO ACID RECEPTORS |
1991 |
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1991 |
- Tomas Dzhozef Kress[Us]
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1994 |
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1992 |
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- Nikolas Dzhejms Bech
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SU627757A3 |
| CEPHALOSPORIN DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL COMPOSITION |
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RU2104280C1 |
