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2 087 146

(13)

C1

(51)

IPC

(21) (22)

Application

93015116/14, 1993-03-23

(22)

Actual filing date

1993-03-23

(45)

Published

1997-08-20

(72)

Inventor

Shkurupij V.A.Kurunov Ju.N.Chernova T.G.

(73)

Holder

Novosibirskij Meditsinskij Institut

METHOD OF TREATMENT THE GENERAL TUBERCULOSIS PROCESS IN EXPERIMENT Russian patent published in 1997 - IPC

Abstract RU 2087146 C1

FIELD: experimental medicine. SUBSTANCE: method involves intraperitoneal administration of complex compound of isoniazid and dextran dialdehyde (dextran dialdehyde isonicotinoyl hydrazone) to experimental animals at dose 14 mg/1 kg body mass. Complex compound is synthesized by dextran oxidation with sodium periodate to dextran dialdehyde and reaction is terminated with 100% ethylene glycol followed by stabilization of Schiff's base with sodium boron hydrate in the end product. EFFECT: enhanced effectiveness of treatment, decreased toxic damage of liver.

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RU 2 087 146 C1

Authors

Shkurupij V.A.

Kurunov Ju.N.

Chernova T.G.

Dates

1997-08-20—Published

1993-03-23—Filed

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