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2 185 166

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IPC

(21) (22)

Application

2000108229/14, 2000-04-03

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Start date

2000-04-03

(22)

Actual filing date

2000-04-03

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Published

2002-07-20

(72)

Inventor

Shkurupij V.A.Kurunov Ju.N.Pupyshev A.B.Panasenko S.G.Kozjaev M.A.Shorina G.N.

(73)

Holder

Novosibirskaja Gosudarstvennaja Meditsinskaja Akademija

AGENT FOR TREATMENT OF TUBERCULOSIS WITH LOW LEVEL OF FIBROTIC COMPLICATIONS Russian patent published in 2002 - IPC

Abstract RU 2185166 C2

FIELD: medicine, phthisiology. SUBSTANCE: invention relates to an agent for treatment of tuberculosis with low level of fibrotic complications that presents a conjugate of isoniazide-dextran of molecular mass 65-75 kDa of the formula: where R1 is H, glucose residue or polyglucosyl residue of the formula given in picture above; R2 is isoniazide residue of the formula: or hydroxyl-group. Agent shows the significantly less level of fibrotic complications as compared with isoniazide-dextran of molecular mass 40 kDa in using in equal doses by isoniazide and similar schedule treatment. EFFECT: improved curative properties, decreased complications in treatment. 2 dwg

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RU 2 185 166 C2

Authors

Shkurupij V.A.

Kurunov Ju.N.

Pupyshev A.B.

Panasenko S.G.

Kozjaev M.A.

Shorina G.N.

Dates

2002-07-20—Published

2000-04-03—Filed

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