FIELD: immunology, microbiology. SUBSTANCE: microorganism Citrobacter freundii or Salmonella typhi is cultured on nutrient medium, supernatant is separated and sterilized by microfiltration on membranes (pore size is 0.22 mc). Filtrate is concentrated, ultracentrifuged, treated with enzymes and subjected for gel-chromatorgaphy. The end product is used for making preparations used for immunodiagnosis and immunoprophylaxis of typhoid fever. EFFECT: high yield, purity and quality of VI-antigen.
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| VACCINE PREPARATION FOR TYPHOID FEVER PROPHYLAXIS | 1997 |
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| Shigella flexneri № 1605-8 BACTERIAL STRAIN, SEROTYPE 2a, DEPOSITED IN FEDERAL STATE INSTITUTION TARASEVICH STATE INSTITUTION OF STANDARTISATION AND CONTROL, NO 285, STABLE S-LIPOPOLYSACCHARIDE PRODUCER | 2009 |
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| METHOD OF PREPARING MENINGOCOCCUS LIPOPOLYSACCHARIDE OF SEROGROUP B | 1993 |
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