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(19)

RU

(11)

2 089 216

(13)

C1

(51)

IPC

(21) (22)

Application

4355806/13, 1988-05-20

(22)

Actual filing date

1988-05-20

(45)

Published

1997-09-10

(72)

Inventor

Isao Fudzita[Jp]Khideo Vatanabe[Jp]Masatosi Mijamoto[Jp]

(73)

Holder

Takeda Kemikal Indastriz Ltd.

METHOD OF REMOVING ENDOTOXIN FROM THE STRAIN BORDETELLA PERTUSSIS CULTURAL FLUID PHASE I Russian patent published in 1997 - IPC

Abstract RU 2089216 C1

FIELD: biotechnology, microbiology. SUBSTANCE: method involves addition of calcium ions in the presence of phosphate ions to liquid containing antiinfectious fraction and endotoxin of strains Bordetella pertussis at phase I. Addition is carried out before zonal centrifugation. EFFECT: increased yield and purity of endotoxin. 2 dwg, 4 tbl

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RU 2 089 216 C1

Authors

Isao Fudzita[Jp]

Khideo Vatanabe[Jp]

Masatosi Mijamoto[Jp]

Dates

1997-09-10—Published

1988-05-20—Filed

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