IPV-DPT VACCINE Russian patent published in 2012 - IPC A61K39/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of invention refers to method for producing vaccines and concerns a method for producing a combined vaccine containing an inactivated Sabin poliovirus strain, a protective Bordetella pertussis antigen, diphtheria toxoid and tetanus toxoid that involves the stage of producing the high titre Sabin poliovirus strain. What is specifically described is a method for producing a combined vaccine involving the stage of cultivating the Vero cells inoculated in the Sabin poliovirus strain in the presence of approximately 4 g/l to approximately 6 g/l of the microcarrier.

EFFECT: group of inventions is applicable for effective preparations of the combined vaccine containing the Sabin poliovirus strain.

11 cl, 1 tbl, 10 ex, 2 dwg